About Prednisone Medication
Prednisone to insulin is one of the most important medical problems. The drug cannot be canceled, since patients with diabetes cannot do without it (with the exception of those who take pills for this disease). The problem can be solved due to hyposensitizing treatment (it is aimed at reducing the manifestations of this pathological condition) and the emergence of new forms of insulin that can be mutually replaced. The currently used varieties of this drug cause allergic reactions with approximately the same frequency - when replacing insulin with its other type, the development of a repeated allergic reaction is not excluded.
Nevertheless, there is a tendency to reduce allergic reactions with the use of more thoroughly purified preparations. This pattern indicates that a significant role in the emergenceBiological additives play a role in the development of the described disease.
Now this question has no practical significance, since combined insulins are not currently used. An allergic reaction to insulin can occur regardless of the onset and duration of action of insulins (according to this characteristic, they are divided into short-acting and prolonged drugs, the latter, in turn, are of medium, long-term and extra-long action).
At the same time, clinicians stated an allergy to both monospecies insulins (they contain an extract of the pancreas of animals of only one species) and combined ones (they are made from extracts of the pancreas of animals of various species). It has been previously suggested that the combination of insulins increases the risk of an allergic reaction, but this has not been statistically confirmed.
In addition to protein impurities, insulin contains inorganic elements (for example, zinc), which can also cause an allergic reaction. As expected, allergic reactions occur less frequently with the use of human insulin, they are less pronounced than after administration of its analogues derived from the pancreas of animals. Bovine insulin is known for the most severe allergic reactions to it.