Order prednisone 20mg - dr. Murphy

If the manifestations persist for a long time and become worse each time, then it is necessary to start taking prednisone pills antihistamine drugs, such as diphenhydramine and suprastin. Injections are made more often, in different parts of the body, the dosage is reduced. If this does not help, then bovine or porcine insulin is replaced with purified human insulin, which does not contain zinc.

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In case of a systemic reaction, adrenaline, antihistamines are urgently administered, as well as placement in a hospital, where respiratory and circulatory support will be provided. Since it is impossible to completely abandon the use of the drug for a diabetic patient, the dosage is temporarily reduced several times, and then gradually. After stabilization of the condition, a gradual (usually two days) return to the previous norm is made.

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If, due to anaphylactic shock, the drug was completely canceled, then before resuming treatment, the following is recommended: Perform trials of all drug options. Choose the appropriate one (causing less consequences) Try the lowest dose. Increase the dose slowly, monitoring the patient's condition with a blood test.

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Some of these symptoms may not indicate an allergy, but an overdose of the drug. Tremor of the fingers. Rapid pulse. Night sweats. Morning headache. Depression.

If it is necessary to reduce the dosage, the patient is prescribed a low-carbohydrate diet, in which everything, including complex carbohydrates, are consumed in limited quantities. All foods that can provoke or exacerbate allergies are excluded from the diet, these include: Milk, eggs, cheese. Honey, coffee, alcohol. Smoked, canned, spicy. Tomatoes, eggplant, red pepper. Caviar and seafood. Dairy drinks. Cottage cheese. Lean meat. From fish: cod and perch. From vegetables: cabbage, zucchini, cucumbers and broccoli.

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In exceptional cases, an overdose can lead to nocturnal diuresis and enuresis, an increase in appetite and weight, morning hyperglycemia. It is important to remember that allergies can have serious consequences for the body, so it is important to undergo a thorough examination before taking the drug and choose the right type of insulin.


Sensitization of Prednisone online body can occur on various compounds - including insulin, which is used in the treatment of patients with diabetes mellitus. An allergy to insulin means an increased sensitivity not only to insulin itself, but also to the impurities of a different (mainly protein) nature that it contains. Manifestations of this pathology can be local (itching at the injection site of insulin, swelling, pain) and general (discharge from the nose, skin rash, respiratory failure).


The diagnosis is made, taking into account the fact that the patient is treated with insulin, traditional allergological tests are additionally performed. Therapy consists in replacing one form of insulin with another and desensitizing measures.

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Prednisone to insulin is one of the most important medical problems. The drug cannot be canceled, since patients with diabetes cannot do without it (with the exception of those who take pills for this disease). The problem can be solved due to hyposensitizing treatment (it is aimed at reducing the manifestations of this pathological condition) and the emergence of new forms of insulin that can be mutually replaced. The currently used varieties of this drug cause allergic reactions with approximately the same frequency - when replacing insulin with its other type, the development of a repeated allergic reaction is not excluded.


Nevertheless, there is a tendency to reduce allergic reactions with the use of more thoroughly purified preparations. This pattern indicates that a significant role in the emergenceBiological additives play a role in the development of the described disease.

— Dr. Murphy

Now this question has no practical significance, since combined insulins are not currently used. An allergic reaction to insulin can occur regardless of the onset and duration of action of insulins (according to this characteristic, they are divided into short-acting and prolonged drugs, the latter, in turn, are of medium, long-term and extra-long action).

At the same time, clinicians stated an allergy to both monospecies insulins (they contain an extract of the pancreas of animals of only one species) and combined ones (they are made from extracts of the pancreas of animals of various species). It has been previously suggested that the combination of insulins increases the risk of an allergic reaction, but this has not been statistically confirmed.

In addition to protein impurities, insulin contains inorganic elements (for example, zinc), which can also cause an allergic reaction. As expected, allergic reactions occur less frequently with the use of human insulin, they are less pronounced than after administration of its analogues derived from the pancreas of animals. Bovine insulin is known for the most severe allergic reactions to it.

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The local form of allergy to insulin has one characteristic feature - the impetus for its development may be the wrong administration (injection) of insulin. Most often, these are such flaws as: use for injection of a thick needle; its insufficient sharpness (defective needles), which provokes soft tissue trauma at the injection site; the introduction of insulin is not deep into the tissues, but into the thickness of the skin; its introduction to those places that are not intended to perform this procedure; overly pronounced cooling of the insulin that is injected.

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